Although systemic drug therapy was discontinued during the person’s demand, she is still alive. While systemic medicine therapy was stopped, we had been able to verify the pure regional control effect of mixture of radiotherapy and Mohs paste.We present the truth of a 70-year-old lady with disease medical textile affecting an amazing part of her breast, characterized by persistent bleeding from the primary tumor. Pathological findings revealed a hormone-sensitive mucinous carcinoma. CT suggested a primary tumefaction in close proximity to the greater pectoral muscle mass, left axillary lymph node metastasis, and oligometastases in her right lung. Although she declined surgery and chemotherapy, she decided to get Mohs’ paste and endocrine treatment. The paste ended up being applied locally, and neighborhood control had been attained after 2 weeks. Five years later, CR was nonetheless maintained in her remaining breast. Mohs’ paste played a vital role in achieving regional control of the exudation and bleeding through the exposed, unresected cancer. It became a highly skilled part of hormone-sensitive neighborhood treatment, working synergistically with systemic medication therapy and hormone therapy.We report a case of higher level cancer of the breast in an elderly patient effectively treated with locoregional treatment. The in-patient had been an 81-year-old girl which served with an escalating right breast swelling. The cyst had been 55 mm in diameter, combined with fixation to pectoral muscle tissue. A core needle biopsy for correct breast tumor generated a diagnosis of mucinous carcinoma, positive for estrogen receptor(ER)and progesterone receptor(PgR), unfavorable for HER2/neu. The Ki-67 good cellular index ended up being 10%. A bone scintigraphy disclosed several bone tissue metastases, therefore, we confirmed the diagnosis as T4cN2aM1, Stage Ⅳ. She initiated endocrine therapy by letrozole. By changing the hormonal therapy to toremifene accompanied by fulvestrant, the treatment reached a partial response. Nevertheless, how big the main tumor enhanced followed by hemorrhaging, and medical resection of the correct breast ended up being carried out for regional control. The locoregional surgery had been efficient, enhancing the person’s standard of living. She ended up being administered lapatinib as anti-HER2 therapy in addition to the hormonal therapy. 2 yrs and six months after surgery, there is no worsening of bone tissue metastasis or look of visceral metastasis.The patient was a 60s male. He underwent esophagectomy and gastric tube reconstruction for Barrett’s esophageal cancer tumors( pT3N1M0, pStage Ⅲ). Postoperatively, anastomotic leakage and mediastinitis lead to septic surprise. From the 8th time after very first surgery, he transferred to our hospital. At the time of admission, qSOFA was 3 points. We judged to be tough to treat with traditional thylakoid biogenesis therapy. Crisis right thoracotomy drainage underwent with resection associated with the esophagogastric anastomosis and cervical esophagostomy building. He was discharged on the 55th postoperative time with home enteral nutrition. He underwent presternal ileocolic repair from the 97th time after right thoracotomy drainage. Regarding the nineteenth time after repair, dental consumption had been begun. The general condition is good without recurrence, and dental intake is enough at 12 months after reconstruction. We report an incident of anastomotic leakage with septic shock after esophageal disease surgery successfully treated by 2 stage ileocolic reconstruction.A metastatic tumefaction for the umbilicus is called”Sister Mary Joseph’s nodule”, and patients with this tumor show a poor prognosis. Sister Mary Joseph’s nodule is an uncommon event, and there are few case reports. We report an instance of cecal cancer tumors very first served with the metastatic tumor when you look at the umbilicus. A 90-year-old girl, reported umbilical induration and foul-smelling release, was treated as omphalitis for just two months. Because her symptom did not improve, biopsy for the umbilical cyst was done, plus the T-DM1 supplier conclusions revealed an adenocarcinoma. She was regarded our medical center. Stomach CT showed wall thickening when you look at the cecum, and numerous liver metastases. Consequently, we performed lower gastrointestinal endoscopy, which revealed a cecal cyst. We performed biopsy regarding the tumefaction together with results were consistent with adenocarcinoma. According to these results, we diagnosed the umbilical tumefaction as a metastasis from the colorectal cancer tumors. Umbilical resection and ileocecal resection had been performed, and multiple peritoneal metastases had been detected. Article operative course ended up being uneventful, she died 11 months after surgery. Umbilical metastases may intensify the individual’s quality of life; thus, your local resection of umbilicus ended up being suggested positively.The patient ended up being a 90-year-old man. He had been known our division with a diagnosis of ascending colon cancer after lower gastrointestinal endoscopy for an optimistic stool occult blood test. Lower gastrointestinal endoscopy unveiled a sort 1 tumefaction 30 mm in the ascending colon and a kind 3 tumefaction 50 mm within the cecum. Biopsy unveiled Group 5(tub1)for the ascending colon lesion, but Group 2 for the cecum lesion. The in-patient had been medically identified as having overlapping ascending cancer of the colon and cecum disease, and a right hemicolectomy of this colon had been carried out.